Transmembrane protein 31 (TMEM31)
Homo sapiens — UniProt Q5JXX7
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 31 (TMEM31) is a protein from Homo sapiens identified by UniProt accession Q5JXX7, 168 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q5JXX7; gene symbol TMEM31.
- Organism: Homo sapiens.
- Length: 168 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, melanoma and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 31 |
|---|---|
| UniProt accession | Q5JXX7 |
| Gene | TMEM31 |
| Organism | Homo sapiens |
| Length | 168 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- melanoma · score 0.02
- cancer · score 0.02
- metastatic melanoma · score 0.01
- neoplasm · score 0.00
- breast cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5JXX7-F1 | alphafold | PREDICTED | 67.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5JXX7.
Amino-acid sequence (168 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM31?
The strongest Open Targets associations for TMEM31 are neurodegenerative disease, melanoma, cancer, metastatic melanoma and neoplasm.
How long is the TMEM31 protein?
The Homo sapiens TMEM31 protein (UniProt Q5JXX7) is 168 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5JXX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5JXX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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