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Long-chain fatty acid transport protein 3 (SLC27A3)

Homo sapiens — UniProt Q5K4L6

Gene: SLC27A3Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Long-chain fatty acid transport protein 3 (SLC27A3) is a protein from Homo sapiens identified by UniProt accession Q5K4L6, 683 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

  • UniProt accession: Q5K4L6; gene symbol SLC27A3.
  • Organism: Homo sapiens.
  • Length: 683 amino acids.
  • Top disease associations (Open Targets): body height, chronotype measurement and neoplasm.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameLong-chain fatty acid transport protein 3
UniProt accessionQ5K4L6
GeneSLC27A3
OrganismHomo sapiens
Length683 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (41)

Diseases linked to this target (Open Targets).

  • body height · score 0.20
  • chronotype measurement · score 0.19
  • neoplasm · score 0.09
  • glioblastoma multiforme · score 0.08
  • platelet count · score 0.05
  • blood protein measurement · score 0.04
  • glioblastoma · score 0.04
  • exudative vitreoretinopathy 2, X-linked · score 0.03
  • proliferative vitreoretinopathy · score 0.03
  • cancer · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5K4L6-F1alphafoldPREDICTED85.84—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5K4L6.

Amino-acid sequence (683 residues)

MAALLLLPLL LLLPLLLLKL HLWPQLRWLP ADLAFAVRAL CCKRALRARA LAAAAADPEG PEGGCSLAWR LAELAQQRAA HTFLIHGSRR FSYSEAERES NRAARAFLRA LGWDWGPDGG DSGEGSAGEG ERAAPGAGDA AAGSGAEFAG GDGAARGGGA AAPLSPGATV ALLLPAGPEF LWLWFGLAKA GLRTAFVPTA LRRGPLLHCL RSCGARALVL APEFLESLEP DLPALRAMGL HLWAAGPGTH PAGISDLLAE VSAEVDGPVP GYLSSPQSIT DTCLYIFTSG TTGLPKAARI SHLKILQCQG FYQLCGVHQE DVIYLALPLY HMSGSLLGIV GCMGIGATVV LKSKFSAGQF WEDCQQHRVT VFQYIGELCR YLVNQPPSKA ERGHKVRLAV GSGLRPDTWE RFVRRFGPLQ VLETYGLTEG NVATINYTGQ RGAVGRASWL YKHIFPFSLI RYDVTTGEPI RDPQGHCMAT SPGEPGLLVA PVSQQSPFLG YAGGPELAQG KLLKDVFRPG DVFFNTGDLL VCDDQGFLRF HDRTGDTFRW KGENVATTEV AEVFEALDFL QEVNVYGVTV PGHEGRAGMA ALVLRPPHAL DLMQLYTHVS ENLPPYARPR FLRLQESLAT TETFKQQKVR MANEGFDPST LSDPLYVLDQ AVGAYLPLTT ARYSALLAGN LRI

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC27A3?

The strongest Open Targets associations for SLC27A3 are body height, chronotype measurement, neoplasm, glioblastoma multiforme and platelet count.

How long is the SLC27A3 protein?

The Homo sapiens SLC27A3 protein (UniProt Q5K4L6) is 683 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5K4L6
GeneSLC27A3
OrganismHomo sapiens
Length683
Binders0
Diseases41
View on UniProt