Collectin-12 (COLEC12)
Homo sapiens — UniProt Q5KU26
Data last refreshed: (UniProt release unknown)
Key facts
Collectin-12 (COLEC12) is a protein from Homo sapiens identified by UniProt accession Q5KU26, 742 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q5KU26; gene symbol COLEC12.
- Organism: Homo sapiens.
- Length: 742 amino acids.
- Top disease associations (Open Targets): blood protein measurement, body height and drug use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Collectin-12 |
|---|---|
| UniProt accession | Q5KU26 |
| Gene | COLEC12 |
| Organism | Homo sapiens |
| Length | 742 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.34
- body height · score 0.33
- drug use measurement · score 0.32
- total blood protein measurement · score 0.32
- cortical surface area measurement · score 0.28
- PHF-tau measurement · score 0.25
- squamous cell lung carcinoma · score 0.23
- head and neck squamous cell carcinoma · score 0.19
- lung adenocarcinoma · score 0.19
- glioblastoma multiforme · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5KU26-F1 | alphafold | PREDICTED | 69.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5KU26.
Amino-acid sequence (742 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COLEC12?
The strongest Open Targets associations for COLEC12 are blood protein measurement, body height, drug use measurement, total blood protein measurement and cortical surface area measurement.
How long is the COLEC12 protein?
The Homo sapiens COLEC12 protein (UniProt Q5KU26) is 742 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5KU26 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5KU26 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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