Cytospin-B (SPECC1)
Homo sapiens — UniProt Q5M775
Data last refreshed: (UniProt release unknown)
Key facts
Cytospin-B (SPECC1) is a protein from Homo sapiens identified by UniProt accession Q5M775, 1068 residues long. MolForge cross-references it against 0 known binders and 171 disease associations.
- UniProt accession: Q5M775; gene symbol SPECC1.
- Organism: Homo sapiens.
- Length: 1068 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, reticulocyte count and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytospin-B |
|---|---|
| UniProt accession | Q5M775 |
| Gene | SPECC1 |
| Organism | Homo sapiens |
| Length | 1068 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (171)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.49
- reticulocyte count · score 0.46
- erythrocyte count · score 0.45
- mean corpuscular hemoglobin concentration · score 0.44
- mean corpuscular hemoglobin · score 0.43
- self reported educational attainment · score 0.40
- mathematical ability · score 0.40
- hemoglobin measurement · score 0.39
- schizophrenia · score 0.39
- reticulocyte measurement · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5M775-F1 | alphafold | PREDICTED | 66.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5M775.
Amino-acid sequence (1068 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPECC1?
The strongest Open Targets associations for SPECC1 are mean corpuscular volume, reticulocyte count, erythrocyte count, mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin.
How long is the SPECC1 protein?
The Homo sapiens SPECC1 protein (UniProt Q5M775) is 1068 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5M775 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5M775 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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