Coiled-coil domain-containing protein 158 (CCDC158)
Homo sapiens — UniProt Q5M9N0
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 158 (CCDC158) is a protein from Homo sapiens identified by UniProt accession Q5M9N0, 1113 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q5M9N0; gene symbol CCDC158.
- Organism: Homo sapiens.
- Length: 1113 amino acids.
- Top disease associations (Open Targets): creatinine measurement, mean corpuscular hemoglobin and cystatin C measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 158 |
|---|---|
| UniProt accession | Q5M9N0 |
| Gene | CCDC158 |
| Organism | Homo sapiens |
| Length | 1113 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.30
- mean corpuscular hemoglobin · score 0.29
- cystatin C measurement · score 0.24
- serum alanine aminotransferase measurement · score 0.13
- C-X-C motif chemokine 10 measurement · score 0.12
- Moderate albuminuria · score 0.11
- serum albumin measurement · score 0.11
- aspartate aminotransferase measurement · score 0.10
- systolic blood pressure · score 0.10
- testosterone measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5M9N0-F1 | alphafold | PREDICTED | 72.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5M9N0.
Amino-acid sequence (1113 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC158?
The strongest Open Targets associations for CCDC158 are creatinine measurement, mean corpuscular hemoglobin, cystatin C measurement, serum alanine aminotransferase measurement and C-X-C motif chemokine 10 measurement.
How long is the CCDC158 protein?
The Homo sapiens CCDC158 protein (UniProt Q5M9N0) is 1113 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5M9N0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5M9N0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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