NKAP-like protein (NKAPL)
Homo sapiens — UniProt Q5M9Q1
Data last refreshed: (UniProt release unknown)
Key facts
NKAP-like protein (NKAPL) is a protein from Homo sapiens identified by UniProt accession Q5M9Q1, 402 residues long. MolForge cross-references it against 0 known binders and 151 disease associations.
- UniProt accession: Q5M9Q1; gene symbol NKAPL.
- Organism: Homo sapiens.
- Length: 402 amino acids.
- Top disease associations (Open Targets): schizophrenia, apolipoprotein B measurement and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NKAP-like protein |
|---|---|
| UniProt accession | Q5M9Q1 |
| Gene | NKAPL |
| Organism | Homo sapiens |
| Length | 402 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (151)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.25
- apolipoprotein B measurement · score 0.24
- low density lipoprotein cholesterol measurement · score 0.24
- body height · score 0.21
- erythrocyte count · score 0.16
- mean reticulocyte volume · score 0.13
- base metabolic rate measurement · score 0.12
- hip circumference · score 0.12
- Red cell distribution width · score 0.11
- lean body mass · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5M9Q1-F1 | alphafold | PREDICTED | 60.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5M9Q1.
Amino-acid sequence (402 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NKAPL?
The strongest Open Targets associations for NKAPL are schizophrenia, apolipoprotein B measurement, low density lipoprotein cholesterol measurement, body height and erythrocyte count.
How long is the NKAPL protein?
The Homo sapiens NKAPL protein (UniProt Q5M9Q1) is 402 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5M9Q1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5M9Q1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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