Sperm protein associated with the nucleus on the X chromosome N3 (SPANXN3)
Homo sapiens — UniProt Q5MJ09
Data last refreshed: (UniProt release unknown)
Key facts
Sperm protein associated with the nucleus on the X chromosome N3 (SPANXN3) is a protein from Homo sapiens identified by UniProt accession Q5MJ09, 141 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: Q5MJ09; gene symbol SPANXN3.
- Organism: Homo sapiens.
- Length: 141 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, creatine kinase measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm protein associated with the nucleus on the X chromosome N3 |
|---|---|
| UniProt accession | Q5MJ09 |
| Gene | SPANXN3 |
| Organism | Homo sapiens |
| Length | 141 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- creatine kinase measurement · score 0.02
- blood protein measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5MJ09-F1 | alphafold | PREDICTED | 63.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5MJ09.
Amino-acid sequence (141 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPANXN3?
The strongest Open Targets associations for SPANXN3 are neurodegenerative disease, creatine kinase measurement and blood protein measurement.
How long is the SPANXN3 protein?
The Homo sapiens SPANXN3 protein (UniProt Q5MJ09) is 141 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5MJ09 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5MJ09 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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