Sperm protein associated with the nucleus on the X chromosome N2 (SPANXN2)
Homo sapiens — UniProt Q5MJ10
Data last refreshed: (UniProt release unknown)
Key facts
Sperm protein associated with the nucleus on the X chromosome N2 (SPANXN2) is a protein from Homo sapiens identified by UniProt accession Q5MJ10, 180 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q5MJ10; gene symbol SPANXN2.
- Organism: Homo sapiens.
- Length: 180 amino acids.
- Top disease associations (Open Targets): creatine kinase measurement, blood protein measurement and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm protein associated with the nucleus on the X chromosome N2 |
|---|---|
| UniProt accession | Q5MJ10 |
| Gene | SPANXN2 |
| Organism | Homo sapiens |
| Length | 180 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- creatine kinase measurement · score 0.02
- blood protein measurement · score 0.02
- neoplasm · score 0.01
- Ito hypomelanosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5MJ10-F1 | alphafold | PREDICTED | 58.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5MJ10.
Amino-acid sequence (180 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPANXN2?
The strongest Open Targets associations for SPANXN2 are creatine kinase measurement, blood protein measurement, neoplasm and Ito hypomelanosis.
How long is the SPANXN2 protein?
The Homo sapiens SPANXN2 protein (UniProt Q5MJ10) is 180 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5MJ10 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5MJ10 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.