C-type lectin domain family 12 member A (CLEC12A)
Homo sapiens — UniProt Q5QGZ9
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 12 member A (CLEC12A) is a protein from Homo sapiens identified by UniProt accession Q5QGZ9, 265 residues long. MolForge cross-references it against 0 known binders and 112 disease associations.
- UniProt accession: Q5QGZ9; gene symbol CLEC12A.
- Organism: Homo sapiens.
- Length: 265 amino acids.
- Top disease associations (Open Targets): blood protein measurement, neutrophil count and eosinophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 12 member A |
|---|---|
| UniProt accession | Q5QGZ9 |
| Gene | CLEC12A |
| Organism | Homo sapiens |
| Length | 265 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (112)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.31
- neutrophil count · score 0.25
- eosinophil count · score 0.23
- leukocyte count · score 0.23
- myeloid white cell count · score 0.13
- acute myeloid leukemia · score 0.11
- Immunodeficiency due to a late component of complements deficiency · score 0.08
- myelodysplastic syndrome · score 0.08
- neoplasm · score 0.08
- acute lymphoblastic leukemia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5QGZ9-F1 | alphafold | PREDICTED | 83.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5QGZ9.
Amino-acid sequence (265 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC12A?
The strongest Open Targets associations for CLEC12A are blood protein measurement, neutrophil count, eosinophil count, leukocyte count and myeloid white cell count.
How long is the CLEC12A protein?
The Homo sapiens CLEC12A protein (UniProt Q5QGZ9) is 265 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5QGZ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5QGZ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.