Histone H2B type 2-F (H2BC18)
Homo sapiens — UniProt Q5QNW6
Data last refreshed: (UniProt release unknown)
Key facts
Histone H2B type 2-F (H2BC18) is a protein from Homo sapiens identified by UniProt accession Q5QNW6, 126 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q5QNW6; gene symbol H2BC18.
- Organism: Homo sapiens.
- Length: 126 amino acids.
- Top disease associations (Open Targets): viral disease, infectious disease and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Histone H2B type 2-F |
|---|---|
| UniProt accession | Q5QNW6 |
| Gene | H2BC18 |
| Organism | Homo sapiens |
| Length | 126 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- viral disease · score 0.50
- infectious disease · score 0.50
- high density lipoprotein cholesterol measurement · score 0.17
- interleukin 6 receptor subunit alpha measurement · score 0.17
- triglyceride measurement · score 0.16
- monocyte count · score 0.15
- blood protein measurement · score 0.12
- age at menopause · score 0.10
- apolipoprotein A 1 measurement · score 0.06
- lymphocyte percentage of leukocytes · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5QNW6-F1 | alphafold | PREDICTED | 87.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5QNW6.
Amino-acid sequence (126 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with H2BC18?
The strongest Open Targets associations for H2BC18 are viral disease, infectious disease, high density lipoprotein cholesterol measurement, interleukin 6 receptor subunit alpha measurement and triglyceride measurement.
How long is the H2BC18 protein?
The Homo sapiens H2BC18 protein (UniProt Q5QNW6) is 126 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5QNW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5QNW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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