Protein phosphatase 1 regulatory subunit 29 (ELFN2)
Homo sapiens — UniProt Q5R3F8
Data last refreshed: (UniProt release unknown)
Key facts
Protein phosphatase 1 regulatory subunit 29 (ELFN2) is a protein from Homo sapiens identified by UniProt accession Q5R3F8, 820 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q5R3F8; gene symbol ELFN2.
- Organism: Homo sapiens.
- Length: 820 amino acids.
- Top disease associations (Open Targets): blood protein measurement, glioblastoma multiforme and autism.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein phosphatase 1 regulatory subunit 29 |
|---|---|
| UniProt accession | Q5R3F8 |
| Gene | ELFN2 |
| Organism | Homo sapiens |
| Length | 820 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.09
- glioblastoma multiforme · score 0.08
- autism · score 0.07
- developmental and epileptic encephalopathy, 9 · score 0.06
- Asperger syndrome · score 0.05
- Autism · score 0.05
- attention deficit hyperactivity disorder · score 0.05
- X-linked non-syndromic intellectual disability · score 0.04
- Intellectual disability - hypotonia - spasticity - sleep disorder · score 0.04
- intellectual disability, autosomal dominant 50 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5R3F8-F1 | alphafold | PREDICTED | 60.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5R3F8.
Amino-acid sequence (820 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELFN2?
The strongest Open Targets associations for ELFN2 are blood protein measurement, glioblastoma multiforme, autism, developmental and epileptic encephalopathy, 9 and Asperger syndrome.
How long is the ELFN2 protein?
The Homo sapiens ELFN2 protein (UniProt Q5R3F8) is 820 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5R3F8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5R3F8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.