About Uncharacterized protein C1orf167
Uncharacterized protein C1orf167 (C1orf167) is a protein
from Homo sapiens identified by UniProt accession
Q5SNV9, 1449 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Uncharacterized protein C1orf167 |
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| UniProt accession | Q5SNV9 |
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| Gene | C1orf167 |
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| Organism | Homo sapiens |
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| Length | 1449 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (53)
Diseases linked to this target (Open Targets).
- alcohol drinking · score 0.35
- diastolic blood pressure · score 0.31
- systolic blood pressure · score 0.28
- midregional pro atrial natriuretic peptide measurement · score 0.24
- homocysteine measurement · score 0.22
- isolated spina bifida · score 0.18
- mean platelet volume · score 0.18
- triglyceride measurement · score 0.16
- alcohol consumption measurement · score 0.13
- homocystinuria due to methylene tetrahydrofolate reductase deficiency · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SNV9-F1 | alphafold | PREDICTED | 47.31 | — |
Amino-acid sequence (1449 residues)
MELRSDASHK ENVSPKPAAL PKPEQRRFRR SLGIGLSGRH DQWVPGCQVE RGGPAATPSP GAVLDQEPCR VQTNLASPGP RLGLALKDTT GQLVNSSFWQ QSNLQSLARR RQGKAREFAI QQSNLSINET SSPHLCPEPG GSSGPHKLPW GPLLSQEPLA RPSSCLRQSG LPAPGTPSGD FRPTEAFAPL DGHTQPGLRS WGGLGSWRSR LVGEPLTLED LAVPSQNQTQ APSRAAVHQL LASVHCLAQE AARLRCQAPQ EPPGAVQQDL WTGGGQPFSA HPQPSQPVLA SSDGRRRRLR GHRETAAFLE TPASLSDSWA QSKLMSPETT LGTRTKDSLN PEQGLPPAHP LGSGDSCSPW SQDGRAQRGD PSLPRGVGSR GTDPCSSAFS NTAWGVSPKQ KGEEGAPRER VHREEERTAF HLSDTVPASS ASKNKAQNIT APESEAICWQ LLSRCFRSWR HLVKRQREPA AAAVALGRWQ LLRKCLQALW LREAQLEAAW GQYTKVLLVR SFREWRNLAL QQKQVQPHMQ AGPGSPPSRR AQGKGLSLGR STVVDPAQRS RLEHTSPGSL REEEIAQRLL SHPRQRTDSR HERVQILQAL QLAVFFLWCQ QKKRARQERE TLRKATRATQ RTGSFPQAWH STAAGVAWVA PLSPQHQRAW LCRCFGAWQQ FVQRGSRYRD HLADRRTGTL RKCLEQWVRM KQLRESDGAK VTQLSLCRQK AGREAVYTAG PGACGLGAVG QAQGQQEQGR GSLQDACWTL ALCWALLLWK MRLFQRQWAN SFFQGLQQRM LQRSLRWWHL RALGPDATSS CTKTPSALEP LSSSTLQDSL EKVPRAPTLP DTLQGSLLWA AGQRQQGQCL LLWQARAQQF QGTARWYQHT RQRRIFLSWS RWATAQWAWR ELASHRAWDR TCRAVLGLWR QRLLQSRLVE WWAQERGWRL ARDALCHWHS CWQGQQFLHE KCQTWVQVHL QGLQKVVFRS WQQAAAHQRC TVTRPEQLLL QSYFQAWCEV VRDTGVLRAQ HQAFQDGLRR RALGAVFATW REAQEVAAGA QEQRVAQASL ARWRSCGQQG QEDGQQKKAR APQAFPAWPV APGMHHEAQQ QAGESAGAQA AQCWTWCWAL WVHESCRGQV SRAHASWKPR AWVLEASVQS AVRGGVQRAI LTQLRPAELR RFLRTVQLRV RLGLPGAGKT RSCWTQATEL VPPAPSLQCS LGGRRKPRGT AWAQRCREHS LCPAFQLWPQ WPGQSSWVPG LPLWTRDQGP RAHSSPEPRA CKAQSKAHKR RLRARSCRIL EKQAQAHGSA LLLALKGHDA LGHQEEVPAA PVPRGTASRA AGFPAGQVPG SGMAALGGCP RGRAAGADPA QGVAPEMGLA DVVAADPATA SGSAVTAAGR WAFKKWHQRL AARSPRRGAA SSPRPWSKPG PKGPESGQEA ARAPRGWGLG AEHGAQLQL
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