Uncharacterized protein C6orf136 (C6orf136)
Homo sapiens — UniProt Q5SQH8
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C6orf136 (C6orf136) is a protein from Homo sapiens identified by UniProt accession Q5SQH8, 315 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q5SQH8; gene symbol C6orf136.
- Organism: Homo sapiens.
- Length: 315 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C6orf136 |
|---|---|
| UniProt accession | Q5SQH8 |
| Gene | C6orf136 |
| Organism | Homo sapiens |
| Length | 315 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- lysosomal storage disease · score 0.31
- mean platelet volume · score 0.18
- functional brain measurement · score 0.12
- brain volume measurement · score 0.12
- BMI-adjusted waist-hip ratio · score 0.03
- monocyte count · score 0.03
- autoimmune thyroid disease · score 0.03
- type 1 diabetes mellitus · score 0.03
- insomnia measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SQH8-F1 | alphafold | PREDICTED | 61.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SQH8.
Amino-acid sequence (315 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C6orf136?
The strongest Open Targets associations for C6orf136 are neurodegenerative disease, lysosomal storage disease, mean platelet volume, functional brain measurement and brain volume measurement.
How long is the C6orf136 protein?
The Homo sapiens C6orf136 protein (UniProt Q5SQH8) is 315 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SQH8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SQH8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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