Alpha-tubulin N-acetyltransferase 1 (ATAT1)
Homo sapiens — UniProt Q5SQI0
Data last refreshed: (UniProt release unknown)
Key facts
Alpha-tubulin N-acetyltransferase 1 (ATAT1) is a protein from Homo sapiens identified by UniProt accession Q5SQI0, 421 residues long. MolForge cross-references it against 0 known binders and 121 disease associations.
- UniProt accession: Q5SQI0; gene symbol ATAT1.
- Organism: Homo sapiens.
- Length: 421 amino acids.
- Top disease associations (Open Targets): lymphocyte count, Myopia and pathological myopia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alpha-tubulin N-acetyltransferase 1 |
|---|---|
| UniProt accession | Q5SQI0 |
| Gene | ATAT1 |
| Organism | Homo sapiens |
| Length | 421 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (121)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.23
- Myopia · score 0.11
- pathological myopia · score 0.11
- mean corpuscular hemoglobin · score 0.11
- platelet count · score 0.11
- leukocyte count · score 0.10
- azoospermia · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- partial chromosome Y deletion · score 0.06
- spermatogenic failure 65 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SQI0-F1 | alphafold | PREDICTED | 68.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SQI0.
Amino-acid sequence (421 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATAT1?
The strongest Open Targets associations for ATAT1 are lymphocyte count, Myopia, pathological myopia, mean corpuscular hemoglobin and platelet count.
How long is the ATAT1 protein?
The Homo sapiens ATAT1 protein (UniProt Q5SQI0) is 421 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SQI0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SQI0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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