Synaptosomal-associated protein 47 (SNAP47)
Homo sapiens — UniProt Q5SQN1
Data last refreshed: (UniProt release unknown)
Key facts
Synaptosomal-associated protein 47 (SNAP47) is a protein from Homo sapiens identified by UniProt accession Q5SQN1, 464 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: Q5SQN1; gene symbol SNAP47.
- Organism: Homo sapiens.
- Length: 464 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and BMI-adjusted waist-hip ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptosomal-associated protein 47 |
|---|---|
| UniProt accession | Q5SQN1 |
| Gene | SNAP47 |
| Organism | Homo sapiens |
| Length | 464 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- body height · score 0.26
- BMI-adjusted waist-hip ratio · score 0.20
- BMI-adjusted waist circumference · score 0.18
- sitting height measurement · score 0.18
- lean body mass · score 0.12
- genetic disorder · score 0.12
- forced expiratory volume · score 0.11
- osteoarthritis, hand · score 0.10
- body fat distribution · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SQN1-F1 | alphafold | PREDICTED | 70.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SQN1.
Amino-acid sequence (464 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNAP47?
The strongest Open Targets associations for SNAP47 are neurodegenerative disease, body height, BMI-adjusted waist-hip ratio, BMI-adjusted waist circumference and sitting height measurement.
How long is the SNAP47 protein?
The Homo sapiens SNAP47 protein (UniProt Q5SQN1) is 464 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SQN1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SQN1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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