Mitochondrial import inner membrane translocase subunit Tim23B (TIMM23B)
Homo sapiens — UniProt Q5SRD1
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial import inner membrane translocase subunit Tim23B (TIMM23B) is a protein from Homo sapiens identified by UniProt accession Q5SRD1, 188 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q5SRD1; gene symbol TIMM23B.
- Organism: Homo sapiens.
- Length: 188 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, glomerular filtration rate and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial import inner membrane translocase subunit Tim23B |
|---|---|
| UniProt accession | Q5SRD1 |
| Gene | TIMM23B |
| Organism | Homo sapiens |
| Length | 188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- glomerular filtration rate · score 0.10
- urate measurement · score 0.07
- bone density · score 0.07
- mean reticulocyte volume · score 0.06
- Alopecia universalis · score 0.05
- hypotrichosis simplex · score 0.04
- trichodysplasia-xeroderma syndrome · score 0.03
- alopecia universalis congenita · score 0.03
- hypotrichosis 4 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SRD1-F1 | alphafold | PREDICTED | 54.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SRD1.
Amino-acid sequence (188 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TIMM23B?
The strongest Open Targets associations for TIMM23B are neurodegenerative disease, glomerular filtration rate, urate measurement, bone density and mean reticulocyte volume.
How long is the TIMM23B protein?
The Homo sapiens TIMM23B protein (UniProt Q5SRD1) is 188 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SRD1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SRD1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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