Tetratricopeptide repeat protein 39A (TTC39A)
Homo sapiens — UniProt Q5SRH9
Data last refreshed: (UniProt release unknown)
Key facts
Tetratricopeptide repeat protein 39A (TTC39A) is a protein from Homo sapiens identified by UniProt accession Q5SRH9, 613 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.
- UniProt accession: Q5SRH9; gene symbol TTC39A.
- Organism: Homo sapiens.
- Length: 613 amino acids.
- Top disease associations (Open Targets): calcium measurement, blood phosphate measurement and lymphocyte percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tetratricopeptide repeat protein 39A |
|---|---|
| UniProt accession | Q5SRH9 |
| Gene | TTC39A |
| Organism | Homo sapiens |
| Length | 613 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (75)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.34
- blood phosphate measurement · score 0.32
- lymphocyte percentage of leukocytes · score 0.31
- mathematical ability · score 0.30
- parathyroid disease · score 0.19
- BMI-adjusted waist-hip ratio · score 0.17
- QRS duration · score 0.15
- Wolff-Parkinson-White Syndrome · score 0.14
- brain volume measurement · score 0.13
- QRS complex · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SRH9-F1 | alphafold | PREDICTED | 86.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SRH9.
Amino-acid sequence (613 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTC39A?
The strongest Open Targets associations for TTC39A are calcium measurement, blood phosphate measurement, lymphocyte percentage of leukocytes, mathematical ability and parathyroid disease.
How long is the TTC39A protein?
The Homo sapiens TTC39A protein (UniProt Q5SRH9) is 613 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SRH9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SRH9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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