Testis-expressed basic protein 1 (TSBP1)
Homo sapiens — UniProt Q5SRN2
Data last refreshed: (UniProt release unknown)
Key facts
Testis-expressed basic protein 1 (TSBP1) is a protein from Homo sapiens identified by UniProt accession Q5SRN2, 563 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q5SRN2; gene symbol TSBP1.
- Organism: Homo sapiens.
- Length: 563 amino acids.
- Top disease associations (Open Targets): eosinophil count, atopic eczema and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Testis-expressed basic protein 1 |
|---|---|
| UniProt accession | Q5SRN2 |
| Gene | TSBP1 |
| Organism | Homo sapiens |
| Length | 563 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.41
- atopic eczema · score 0.37
- leukocyte count · score 0.37
- triglyceride measurement · score 0.32
- cirrhosis of liver · score 0.31
- diastolic blood pressure · score 0.28
- Graves disease · score 0.28
- hepatitis C induced liver cirrhosis · score 0.27
- Eczematoid dermatitis · score 0.26
- drug-induced liver injury · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SRN2-F1 | alphafold | PREDICTED | 45.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SRN2.
Amino-acid sequence (563 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSBP1?
The strongest Open Targets associations for TSBP1 are eosinophil count, atopic eczema, leukocyte count, triglyceride measurement and cirrhosis of liver.
How long is the TSBP1 protein?
The Homo sapiens TSBP1 protein (UniProt Q5SRN2) is 563 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SRN2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SRN2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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