Small integral membrane protein 40 (SMIM40)
Homo sapiens — UniProt Q5STR5
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 40 (SMIM40) is a protein from Homo sapiens identified by UniProt accession Q5STR5, 79 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: Q5STR5; gene symbol SMIM40.
- Organism: Homo sapiens.
- Length: 79 amino acids.
- Top disease associations (Open Targets): interstitial lung disease, inflammatory spondylopathy and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 40 |
|---|---|
| UniProt accession | Q5STR5 |
| Gene | SMIM40 |
| Organism | Homo sapiens |
| Length | 79 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- interstitial lung disease · score 0.11
- inflammatory spondylopathy · score 0.11
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5STR5-F1 | alphafold | PREDICTED | 76.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5STR5.
Amino-acid sequence (79 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM40?
The strongest Open Targets associations for SMIM40 are interstitial lung disease, inflammatory spondylopathy and body height.
How long is the SMIM40 protein?
The Homo sapiens SMIM40 protein (UniProt Q5STR5) is 79 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5STR5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5STR5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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