Transmembrane protein 240 (TMEM240)
Homo sapiens — UniProt Q5SV17
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 240 (TMEM240) is a protein from Homo sapiens identified by UniProt accession Q5SV17, 173 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.
- UniProt accession: Q5SV17; gene symbol TMEM240.
- Organism: Homo sapiens.
- Length: 173 amino acids.
- Top disease associations (Open Targets): spinocerebellar ataxia type 21, Neurodevelopmental disorder and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 240 |
|---|---|
| UniProt accession | Q5SV17 |
| Gene | TMEM240 |
| Organism | Homo sapiens |
| Length | 173 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (85)
Diseases linked to this target (Open Targets).
- spinocerebellar ataxia type 21 · score 0.79
- Neurodevelopmental disorder · score 0.34
- genetic disorder · score 0.19
- serum albumin measurement · score 0.13
- sex hormone-binding globulin measurement · score 0.08
- neoplasm · score 0.07
- neuroferritinopathy · score 0.05
- severe neurodegenerative syndrome with lipodystrophy · score 0.04
- alkaline phosphatase measurement · score 0.04
- cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SV17-F1 | alphafold | PREDICTED | 58.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SV17.
Amino-acid sequence (173 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM240?
The strongest Open Targets associations for TMEM240 are spinocerebellar ataxia type 21, Neurodevelopmental disorder, genetic disorder, serum albumin measurement and sex hormone-binding globulin measurement.
How long is the TMEM240 protein?
The Homo sapiens TMEM240 protein (UniProt Q5SV17) is 173 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SV17 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SV17 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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