Protein SPMIP3 (SPMIP3)

About Protein SPMIP3

Protein SPMIP3 (SPMIP3) is a protein from Homo sapiens identified by UniProt accession Q5SVJ3, 147 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Protein SPMIP3
UniProt accession	Q5SVJ3
Gene	SPMIP3
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

monocyte count · score 0.41
self reported educational attainment · score 0.34
mathematical ability · score 0.34
lymphocyte count · score 0.34
number of siblings · score 0.27
myeloid white cell count · score 0.27
cognitive function measurement · score 0.25
brain volume measurement · score 0.25
uterine fibroid · score 0.23
mean corpuscular volume · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5SVJ3-F1	alphafold	PREDICTED	63.39	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SVJ3.

Amino-acid sequence (147 residues)

MTAIRLREFI ERRPVIPPSI FIAHQGRDVQ GYYPGQLARL HFDHSAKRAP RPLIDLTIPP KTKYHYQPQL DQQTLIRYIC LRRHSKPAEP WYKETTYRRD YSLPFYEIDW NQKLATVSLN PRPLNSLPEL YCCEERSSFE RNAFKLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards