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Zinc finger and BTB domain-containing protein 41 (ZBTB41)

Homo sapiens — UniProt Q5SVQ8

Gene: ZBTB41Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger and BTB domain-containing protein 41 (ZBTB41) is a protein from Homo sapiens identified by UniProt accession Q5SVQ8, 909 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.

  • UniProt accession: Q5SVQ8; gene symbol ZBTB41.
  • Organism: Homo sapiens.
  • Length: 909 amino acids.
  • Top disease associations (Open Targets): blood protein measurement, coagulation factor measurement and body mass index.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger and BTB domain-containing protein 41
UniProt accessionQ5SVQ8
GeneZBTB41
OrganismHomo sapiens
Length909 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (29)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.35
  • coagulation factor measurement · score 0.32
  • body mass index · score 0.30
  • hemopexin measurement · score 0.29
  • systolic blood pressure · score 0.22
  • alkaline phosphatase measurement · score 0.20
  • complement factor H-related protein 1 measurement · score 0.18
  • complement factor H-related protein 3 measurement · score 0.17
  • sex hormone-binding globulin measurement · score 0.15
  • high density lipoprotein cholesterol measurement · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5SVQ8-F1alphafoldPREDICTED61.32—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SVQ8.

Amino-acid sequence (909 residues)

MKKRRKVTSN LEKIHLGYHK DSSEGNVAVE CDQVTYTHSA GRPTPEALHC YQELPPSPDQ RKLLSSLQYN KNLLKYLNDD RQKQPSFCDL LIIVEGKEFS AHKVVVAVGS SYFHACLSKN PSTDVVTLDH VTHSVFQHLL EFLYTSEFFV YKYEIPLVLE AAKFLDIIDA VKLLNNENVA PFHSELTEKS SPEETLNELT GRLSNNHQCK FCSRHFCYKK SLENHLAKTH RSLLLGKKHG LKMLERSFSA RRSKRNRKCP VKFDDTSDDE QESGDGSDNL NQENFDKEKS DRNDSEDPGS EYNAEEDELE EEMSDEYSDI EEQSEKDHND AEEEPEAGDS VGNVHEGLTP VVIQNSNKKI LQCPKCDKTF DRIGKYESHT RVHTGEKPFE CDICHQRYST KSNLTVHRKK HSNETEFHKK EHKCPYCNKL HASKKTLAKH VKRFHPENAQ EFISIKKTKS ESWKCDICKK SFTRRPHLEE HMILHSQDKP FKCTYCEEHF KSRFARLKHQ EKFHLGPFPC DICGRQFNDT GNLKRHIECT HGGKRKWTCF ICGKSVRERT TLKEHLRIHS GEKPHLCSIC GQSFRHGSSY RLHLRVHHDD KRYECDECGK TFIRHDHLTK HKKIHSGEKA HQCEECGKCF GRRDHLTVHY KSVHLGEKVW QKYKATFHQC DVCKKIFKGK SSLEMHFRTH SGEKPYKCQI CNQSFRIKKT LTKHLVIHSD ARPFNCQHCN ATFKRKDKLK YHIDHVHEIK SPDDPLSTSE EKLVSLPVEY SSDDKIFQTE TKQYMDQPKV YQSEAKTMLQ NVSAEVCVPV TLVPVQMPDT PSDLVRHTTT LPPSSHEILS PQPQSTDYPR AADLAFLEKY TLTPQPANIV HPVRPEQMLD PREQSYLGTL LGLDSTTGVQ NISTNEHHS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZBTB41?

The strongest Open Targets associations for ZBTB41 are blood protein measurement, coagulation factor measurement, body mass index, hemopexin measurement and systolic blood pressure.

How long is the ZBTB41 protein?

The Homo sapiens ZBTB41 protein (UniProt Q5SVQ8) is 909 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5SVQ8
GeneZBTB41
OrganismHomo sapiens
Length909
Binders0
Diseases29
View on UniProt