Glycine N-acyltransferase-like protein 3 (GLYATL3)
Homo sapiens — UniProt Q5SZD4
Data last refreshed: (UniProt release unknown)
Key facts
Glycine N-acyltransferase-like protein 3 (GLYATL3) is a protein from Homo sapiens identified by UniProt accession Q5SZD4, 288 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q5SZD4; gene symbol GLYATL3.
- Organism: Homo sapiens.
- Length: 288 amino acids.
- Top disease associations (Open Targets): urinary metabolite measurement, Alzheimer disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycine N-acyltransferase-like protein 3 |
|---|---|
| UniProt accession | Q5SZD4 |
| Gene | GLYATL3 |
| Organism | Homo sapiens |
| Length | 288 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- urinary metabolite measurement · score 0.30
- Alzheimer disease · score 0.27
- multiple sclerosis · score 0.27
- lysosomal storage disease · score 0.27
- neurodegenerative disease · score 0.27
- Parkinson disease · score 0.27
- depressive episode measurement · score 0.09
- mean reticulocyte volume · score 0.08
- mean corpuscular volume · score 0.07
- drug use measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SZD4-F1 | alphafold | PREDICTED | 94.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SZD4.
Amino-acid sequence (288 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLYATL3?
The strongest Open Targets associations for GLYATL3 are urinary metabolite measurement, Alzheimer disease, multiple sclerosis, lysosomal storage disease and neurodegenerative disease.
How long is the GLYATL3 protein?
The Homo sapiens GLYATL3 protein (UniProt Q5SZD4) is 288 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SZD4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SZD4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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