BEN domain-containing protein 6 (BEND6)
Homo sapiens — UniProt Q5SZJ8
Data last refreshed: (UniProt release unknown)
Key facts
BEN domain-containing protein 6 (BEND6) is a protein from Homo sapiens identified by UniProt accession Q5SZJ8, 279 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q5SZJ8; gene symbol BEND6.
- Organism: Homo sapiens.
- Length: 279 amino acids.
- Top disease associations (Open Targets): body height, age at menarche and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BEN domain-containing protein 6 |
|---|---|
| UniProt accession | Q5SZJ8 |
| Gene | BEND6 |
| Organism | Homo sapiens |
| Length | 279 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- body height · score 0.44
- age at menarche · score 0.39
- neurodegenerative disease · score 0.29
- body mass index · score 0.29
- mean corpuscular volume · score 0.15
- erythrocyte count · score 0.10
- red blood cell density measurement · score 0.08
- appendicular lean mass · score 0.08
- hemoglobin measurement · score 0.05
- atypical teratoid rhabdoid tumor · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SZJ8-F1 | alphafold | PREDICTED | 71.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SZJ8.
Amino-acid sequence (279 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BEND6?
The strongest Open Targets associations for BEND6 are body height, age at menarche, neurodegenerative disease, body mass index and mean corpuscular volume.
How long is the BEND6 protein?
The Homo sapiens BEND6 protein (UniProt Q5SZJ8) is 279 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SZJ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SZJ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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