Centrosomal protein of 85 kDa-like (CEP85L)
Homo sapiens — UniProt Q5SZL2
Data last refreshed: (UniProt release unknown)
Key facts
Centrosomal protein of 85 kDa-like (CEP85L) is a protein from Homo sapiens identified by UniProt accession Q5SZL2, 805 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q5SZL2; gene symbol CEP85L.
- Organism: Homo sapiens.
- Length: 805 amino acids.
- Top disease associations (Open Targets): lissencephaly 10, familial isolated dilated cardiomyopathy and hypertrophic cardiomyopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Centrosomal protein of 85 kDa-like |
|---|---|
| UniProt accession | Q5SZL2 |
| Gene | CEP85L |
| Organism | Homo sapiens |
| Length | 805 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- lissencephaly 10 · score 0.73
- familial isolated dilated cardiomyopathy · score 0.56
- hypertrophic cardiomyopathy · score 0.54
- Rare familial disorder with hypertrophic cardiomyopathy · score 0.52
- cardiomyopathy · score 0.51
- Abnormality of the cardiovascular system · score 0.47
- Lissencephaly · score 0.47
- dilated cardiomyopathy · score 0.44
- QT interval · score 0.39
- lissencephaly 9 with complex brainstem malformation · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SZL2-F1 | alphafold | PREDICTED | 64.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SZL2.
Amino-acid sequence (805 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CEP85L?
The strongest Open Targets associations for CEP85L are lissencephaly 10, familial isolated dilated cardiomyopathy, hypertrophic cardiomyopathy, Rare familial disorder with hypertrophic cardiomyopathy and cardiomyopathy.
How long is the CEP85L protein?
The Homo sapiens CEP85L protein (UniProt Q5SZL2) is 805 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SZL2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SZL2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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