CUGBP Elav-like family member 3 (CELF3)
Homo sapiens — UniProt Q5SZQ8
Data last refreshed: (UniProt release unknown)
Key facts
CUGBP Elav-like family member 3 (CELF3) is a protein from Homo sapiens identified by UniProt accession Q5SZQ8, 465 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q5SZQ8; gene symbol CELF3.
- Organism: Homo sapiens.
- Length: 465 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, azoospermia and male infertility with teratozoospermia due to single gene mutation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CUGBP Elav-like family member 3 |
|---|---|
| UniProt accession | Q5SZQ8 |
| Gene | CELF3 |
| Organism | Homo sapiens |
| Length | 465 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- azoospermia · score 0.09
- male infertility with teratozoospermia due to single gene mutation · score 0.09
- spermatogenic failure 7 · score 0.07
- spermatogenic failure 70 · score 0.07
- spermatogenic failure 10 · score 0.07
- spermatogenic failure 11 · score 0.07
- partial chromosome Y deletion · score 0.07
- spermatogenic failure 47 · score 0.07
- spermatogenic failure 64 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5SZQ8-F1 | alphafold | PREDICTED | 70.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5SZQ8.
Amino-acid sequence (465 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CELF3?
The strongest Open Targets associations for CELF3 are neurodegenerative disease, azoospermia, male infertility with teratozoospermia due to single gene mutation, spermatogenic failure 7 and spermatogenic failure 70.
How long is the CELF3 protein?
The Homo sapiens CELF3 protein (UniProt Q5SZQ8) is 465 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5SZQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5SZQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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