Coiled-coil and C2 domain-containing protein 1B (CC2D1B)
Homo sapiens — UniProt Q5T0F9
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil and C2 domain-containing protein 1B (CC2D1B) is a protein from Homo sapiens identified by UniProt accession Q5T0F9, 858 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q5T0F9; gene symbol CC2D1B.
- Organism: Homo sapiens.
- Length: 858 amino acids.
- Top disease associations (Open Targets): body height, hemoglobin D disease and dominant beta-thalassemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil and C2 domain-containing protein 1B |
|---|---|
| UniProt accession | Q5T0F9 |
| Gene | CC2D1B |
| Organism | Homo sapiens |
| Length | 858 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- body height · score 0.20
- hemoglobin D disease · score 0.05
- dominant beta-thalassemia · score 0.04
- delta-beta-thalassemia · score 0.04
- hemoglobin E disease · score 0.04
- hemoglobin C-beta-thalassemia syndrome · score 0.04
- alpha-thalassemia-myelodysplastic syndrome · score 0.04
- Alpha-thalassemia - myelodysplastic syndrome · score 0.04
- hemoglobin E-beta-thalassemia syndrome · score 0.04
- hemoglobin H disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T0F9-F1 | alphafold | PREDICTED | 70.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T0F9.
Amino-acid sequence (858 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CC2D1B?
The strongest Open Targets associations for CC2D1B are body height, hemoglobin D disease, dominant beta-thalassemia, delta-beta-thalassemia and hemoglobin E disease.
How long is the CC2D1B protein?
The Homo sapiens CC2D1B protein (UniProt Q5T0F9) is 858 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T0F9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T0F9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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