Formin-binding protein 1-like (FNBP1L)
Homo sapiens — UniProt Q5T0N5
Data last refreshed: (UniProt release unknown)
Key facts
Formin-binding protein 1-like (FNBP1L) is a protein from Homo sapiens identified by UniProt accession Q5T0N5, 605 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q5T0N5; gene symbol FNBP1L.
- Organism: Homo sapiens.
- Length: 605 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cortical surface area measurement and serum alanine aminotransferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Formin-binding protein 1-like |
|---|---|
| UniProt accession | Q5T0N5 |
| Gene | FNBP1L |
| Organism | Homo sapiens |
| Length | 605 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- cortical surface area measurement · score 0.37
- serum alanine aminotransferase measurement · score 0.31
- cortical thickness · score 0.30
- brain measurement · score 0.30
- triglyceride measurement · score 0.30
- BMI-adjusted hip circumference · score 0.16
- glomerular filtration rate · score 0.16
- myeloid white cell count · score 0.15
- creatinine measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T0N5-F1 | alphafold | PREDICTED | 79.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T0N5.
Amino-acid sequence (605 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FNBP1L?
The strongest Open Targets associations for FNBP1L are neurodegenerative disease, cortical surface area measurement, serum alanine aminotransferase measurement, cortical thickness and brain measurement.
How long is the FNBP1L protein?
The Homo sapiens FNBP1L protein (UniProt Q5T0N5) is 605 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T0N5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T0N5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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