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Coiled-coil domain-containing protein 122 (CCDC122)

Homo sapiens — UniProt Q5T0U0

Gene: CCDC122Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Coiled-coil domain-containing protein 122 (CCDC122) is a protein from Homo sapiens identified by UniProt accession Q5T0U0, 273 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

  • UniProt accession: Q5T0U0; gene symbol CCDC122.
  • Organism: Homo sapiens.
  • Length: 273 amino acids.
  • Top disease associations (Open Targets): leprosy, inflammatory bowel disease and Crohn's disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCoiled-coil domain-containing protein 122
UniProt accessionQ5T0U0
GeneCCDC122
OrganismHomo sapiens
Length273 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (25)

Diseases linked to this target (Open Targets).

  • leprosy · score 0.29
  • inflammatory bowel disease · score 0.28
  • Crohn's disease · score 0.28
  • schizophrenia · score 0.26
  • asthma · score 0.25
  • intelligence · score 0.25
  • self reported educational attainment · score 0.25
  • psoriasis · score 0.24
  • creatinine measurement · score 0.23
  • ankylosing spondylitis · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T0U0-F1alphafoldPREDICTED88.86—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T0U0.

Amino-acid sequence (273 residues)

MSDNKERKSQ GFPKEDNQDT SSLADAVEKV AKQQQSQASE IEKNKKVLFN LKNELHELEK EIAAISAETK ETERQIYQQD SAIENTKLHC DSLETQIKSL HSENVKLKFD IETAQEDFEE HMIKYNAYYA KIKAHKNSLG EVESKWSFMT ELHEKRDFVK KLKTMKEELM QDLQNPGGNR ITQVQEDITN LKDKIITVKE SIIEKTCFLE EEKKTHEKLR KEIEVQHKRY DAILKRLHCQ VNKLQSNRRQ WQWNIQQLEK TAAELRKCIG MQE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC122?

The strongest Open Targets associations for CCDC122 are leprosy, inflammatory bowel disease, Crohn's disease, schizophrenia and asthma.

How long is the CCDC122 protein?

The Homo sapiens CCDC122 protein (UniProt Q5T0U0) is 273 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T0U0
GeneCCDC122
OrganismHomo sapiens
Length273
Binders0
Diseases25
View on UniProt