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Protein FAM83B (FAM83B)

Homo sapiens — UniProt Q5T0W9

Gene: FAM83BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein FAM83B (FAM83B) is a protein from Homo sapiens identified by UniProt accession Q5T0W9, 1011 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.

  • UniProt accession: Q5T0W9; gene symbol FAM83B.
  • Organism: Homo sapiens.
  • Length: 1011 amino acids.
  • Top disease associations (Open Targets): age at menarche, chronotype measurement and potassium measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein FAM83B
UniProt accessionQ5T0W9
GeneFAM83B
OrganismHomo sapiens
Length1011 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (59)

Diseases linked to this target (Open Targets).

  • age at menarche · score 0.36
  • chronotype measurement · score 0.32
  • potassium measurement · score 0.27
  • adolescent idiopathic scoliosis · score 0.18
  • PHF-tau measurement · score 0.17
  • glomerular filtration rate · score 0.16
  • blood urea nitrogen measurement · score 0.16
  • creatinine measurement · score 0.16
  • sleep duration · score 0.15
  • fat body mass · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T0W9-F1alphafoldPREDICTED51.22—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T0W9.

Amino-acid sequence (1011 residues)

METSSMLSSL NDECKSDNYI EPHYKEWYRV AIDILIEHGL EAYQEFLVQE RVSDFLAEEE INYILKNVQK VAQSTAHGTD DSCDDTLSSG TYWPVESDVE APNLDLGWPY VMPGLLGGTH IDLLFHPPRA HLLTIKETIR KMIKEARKVI ALVMDIFTDV DIFKEIVEAS TRGVSVYILL DESNFNHFLN MTEKQGCSVQ RLRNIRVRTV KGQDYLSKTG AKFHGKMEQK FLLVDCQKVM YGSYSYMWSF EKAHLSMVQI ITGQLVESFD EEFRTLYARS CVPSSFAQEE SARVKHGKAL WENGTYQHSV SSLASVSSQR NLFGRQDKIH KLDSSYFKNR GIYTLNEHDK YNIRSHGYKP HFVPNFNGPN AIRQFQPNQI NENWKRHSYA GEQPETVPYL LLNRALNRTN NPPGNWKKPS DSLSVASSSR EGYVSHHNTP AQSFANRLAQ RKTTNLADRN SNVRRSFNGT DNHIRFLQQR MPTLEHTTKS FLRNWRIESY LNDHSEATPD SNGSALGDRF EGYDNPENLK ANALYTHSRL RSSLVFKPTL PEQKEVNSCT TGSSNSTIIG SQGSETPKEV PDTPTNVQHL TDKPLPESIP KLPLQSEAPK MHTLQVPENH SVALNQTTNG HTESNNYIYK TLGVNKQTEN LKNQQTENLL KRRSFPLFDN SKANLDPGNS KHYVYSTLTR NRVRQPEKPK EDLLKSSKSM HNVTHNLEED EEEVTKRNSP SGTTTKSVSI AALLDVNKEE SNKELASKKE VKGSPSFLKK GSQKLRSLLS LTPDKKENLS KNKAPAFYRL CSSSDTLVSE GEENQKPKKS DTKVDSSPRR KHSSSSNSQG SIHKSKEDVT VSPSQEINAP PDENKRTPSP GPVESKFLER AGDASAPRFN TEQIQYRDSR EINAVVTPER RPTSSPRPTS SELLRSHSTD RRVYSRFEPF CKIESSIQPT SNMPNTSINR PEIKSATMGN SYGRSSPLLN YNTGVYRSYQ PNENKFRGFM QKFGNFIHKN K

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAM83B?

The strongest Open Targets associations for FAM83B are age at menarche, chronotype measurement, potassium measurement, adolescent idiopathic scoliosis and PHF-tau measurement.

How long is the FAM83B protein?

The Homo sapiens FAM83B protein (UniProt Q5T0W9) is 1011 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T0W9
GeneFAM83B
OrganismHomo sapiens
Length1011
Binders0
Diseases59
View on UniProt