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Uncharacterized protein C6orf132 (C6orf132)

Homo sapiens — UniProt Q5T0Z8

Gene: C6orf132Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C6orf132 (C6orf132) is a protein from Homo sapiens identified by UniProt accession Q5T0Z8, 1188 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

  • UniProt accession: Q5T0Z8; gene symbol C6orf132.
  • Organism: Homo sapiens.
  • Length: 1188 amino acids.
  • Top disease associations (Open Targets): esophageal squamous cell carcinoma, whole body water mass and erythrocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C6orf132
UniProt accessionQ5T0Z8
GeneC6orf132
OrganismHomo sapiens
Length1188 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (12)

Diseases linked to this target (Open Targets).

  • esophageal squamous cell carcinoma · score 0.03
  • whole body water mass · score 0.02
  • erythrocyte count · score 0.02
  • Thymoma · score 0.01
  • oral squamous cell carcinoma · score 0.01
  • rosacea · score 0.01
  • sessile serrated polyp · score 0.00
  • reading · score 0.00
  • cutaneous lupus erythematosus · score 0.00
  • pancreatic carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T0Z8-F1alphafoldPREDICTED47.26—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T0Z8.

Amino-acid sequence (1188 residues)

MKKKQTVQGT FSKLFGKKHT TTPSTSLYAT NPPWIFTQEA PEEGTGGFDG IYYGDNRFNT VSESGTATLK ARPRVRPLLT FLPLNAQENH GLAVPTPSVP DDFADKEVTG TSSLVNGNLR LYSSVGDLRP GQYGQDLLIP PPPPGPAPGP PQDISEPPGG SPLPSPPSTA PPPPPLLLEP PPPPSMAPPP PPVLEALSPP HTLSSPSIPT PPDFIPPAPP LAFLAPPPPP VPAPAPPAPA SPHTVGTRLF PPGGVTKWKS DVALNGRQAE ATRASPPRSP AEPKGSALGP NPEPHLTFPR SFKVPPPTPV RTSSIPVQEA QEAPRKEEGA TKKAPSRLPL PPSFHIRPAS QVYPDRAPEP DCPGELKATA PASPRLGQSQ SQADERAGTP PPAPPLPPPA PPLPPPAPPL PPAAPPLPCA QKAAHPPAGF TKTPKSSSPA LKPKPNPPSP ENTASSAPVD WRDPSQMEKL RNELAAYLCG SRREDRFLSH RPGPTVAPQS KEGKKGPRLP EKETLLSLPA KDTPPGVPEK SLGGSSLTET EAAPSLTLPS VDYIPQDSPT PSVRQIRNEL EARLSSAAEK EAKPSIGSLP PKPRLEGGRI CENGADDDKL SKPVAKNLPP QSTTLLPTTS LQPKAMLGPA IPPKATPEPA IPPKATLWPA TPPKATLGPA TPLKATSGPT TPLKATSGPA IASTATTLPT TTSQLMAEKD SGPAGQPEKP ASQEVSTPSQ ARGEGSPSEA TRLPTQGARS SAAFPPKTSP GGGEVPCLYK PHCHQSSLSR EVAVVMPTLA RGGAAGPGEP VEVKEPPGLP AKPPASAQPT DELLRHPVTG EVVERGSPMA LLLAARQRAQ KGRSVGAALG RSSLPGSLRD HSHQAEASSD SIFHSQGTPN SFTVVPKLPK EAEKDSPLTT EIPNKWGPRL GRDAEGTELS RRHNWTKPEP QAPVAWERVA PSNLPQGHPL PKSFSSPPSP SNKREEEEEE FNFEVIPPPP EFSNDPEPPA PALQYLGRQS SPPRNNYSDL RQLPNAGPGA PPALGFSRFP AGARYAGAGG LERFSGGGRS LIKKRLYVGE PHRGPGLPHG GTGRSLSSPN CFGPQPGGPE MRRVNSAGRA PPGGLHAPRL SLEGAARGAA EAKHKAPGSA DYGFAPAAGR SPYTTTRYGS PINTFTVRPG TRHPISYVCS GAHRKATS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C6orf132?

The strongest Open Targets associations for C6orf132 are esophageal squamous cell carcinoma, whole body water mass, erythrocyte count, Thymoma and oral squamous cell carcinoma.

How long is the C6orf132 protein?

The Homo sapiens C6orf132 protein (UniProt Q5T0Z8) is 1188 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T0Z8
GeneC6orf132
OrganismHomo sapiens
Length1188
Binders0
Diseases12
View on UniProt