DC-STAMP domain-containing protein 2 (DCST2)
Homo sapiens — UniProt Q5T1A1
Data last refreshed: (UniProt release unknown)
Key facts
DC-STAMP domain-containing protein 2 (DCST2) is a protein from Homo sapiens identified by UniProt accession Q5T1A1, 773 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.
- UniProt accession: Q5T1A1; gene symbol DCST2.
- Organism: Homo sapiens.
- Length: 773 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, lean body mass and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DC-STAMP domain-containing protein 2 |
|---|---|
| UniProt accession | Q5T1A1 |
| Gene | DCST2 |
| Organism | Homo sapiens |
| Length | 773 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (120)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.36
- lean body mass · score 0.35
- appendicular lean mass · score 0.33
- birth weight · score 0.32
- waist-hip ratio · score 0.32
- body weight · score 0.30
- cutaneous melanoma · score 0.28
- fat body mass · score 0.28
- eosinophil count · score 0.28
- BMI-adjusted waist circumference · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T1A1-F1 | alphafold | PREDICTED | 73.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T1A1.
Amino-acid sequence (773 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DCST2?
The strongest Open Targets associations for DCST2 are BMI-adjusted waist-hip ratio, lean body mass, appendicular lean mass, birth weight and waist-hip ratio.
How long is the DCST2 protein?
The Homo sapiens DCST2 protein (UniProt Q5T1A1) is 773 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T1A1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T1A1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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