Protein AKNAD1 (AKNAD1)
Homo sapiens — UniProt Q5T1N1
Data last refreshed: (UniProt release unknown)
Key facts
Protein AKNAD1 (AKNAD1) is a protein from Homo sapiens identified by UniProt accession Q5T1N1, 836 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q5T1N1; gene symbol AKNAD1.
- Organism: Homo sapiens.
- Length: 836 amino acids.
- Top disease associations (Open Targets): Chudley-McCullough syndrome, Rare genetic deafness and deafness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein AKNAD1 |
|---|---|
| UniProt accession | Q5T1N1 |
| Gene | AKNAD1 |
| Organism | Homo sapiens |
| Length | 836 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- Chudley-McCullough syndrome · score 0.56
- Rare genetic deafness · score 0.49
- deafness · score 0.48
- hearing loss, autosomal recessive · score 0.46
- genetic disorder · score 0.41
- retinitis pigmentosa 32 · score 0.33
- neurodegenerative disease · score 0.32
- leukocyte count · score 0.16
- Hearing impairment · score 0.12
- neurofibrillary tangles measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T1N1-F1 | alphafold | PREDICTED | 49.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T1N1.
Amino-acid sequence (836 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AKNAD1?
The strongest Open Targets associations for AKNAD1 are Chudley-McCullough syndrome, Rare genetic deafness, deafness, hearing loss, autosomal recessive and genetic disorder.
How long is the AKNAD1 protein?
The Homo sapiens AKNAD1 protein (UniProt Q5T1N1) is 836 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T1N1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T1N1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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