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Solute carrier family 35 member F1 (SLC35F1)

Homo sapiens — UniProt Q5T1Q4

Gene: SLC35F1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Solute carrier family 35 member F1 (SLC35F1) is a protein from Homo sapiens identified by UniProt accession Q5T1Q4, 408 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

  • UniProt accession: Q5T1Q4; gene symbol SLC35F1.
  • Organism: Homo sapiens.
  • Length: 408 amino acids.
  • Top disease associations (Open Targets): resting heart rate, atrial fibrillation and QRS duration.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSolute carrier family 35 member F1
UniProt accessionQ5T1Q4
GeneSLC35F1
OrganismHomo sapiens
Length408 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (47)

Diseases linked to this target (Open Targets).

  • resting heart rate · score 0.40
  • atrial fibrillation · score 0.37
  • QRS duration · score 0.33
  • hypertension · score 0.33
  • diastolic blood pressure · score 0.30
  • blood pressure · score 0.27
  • cardiovascular measurement · score 0.26
  • heel bone mineral density · score 0.26
  • lean body mass · score 0.23
  • systolic blood pressure · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T1Q4-F1alphafoldPREDICTED78.02—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T1Q4.

Amino-acid sequence (408 residues)

MIPPEQPQQQ LQPPSPAPPN HVVTTIENLP AEGSGGGGSL SASSRAGVRQ RIRKVLNREM LISVALGQVL SLLICGIGLT SKYLSEDFHA NTPVFQSFLN YILLFLVYTT TLAVRQGEEN LLAILRRRWW KYMILGLIDL EANYLVVKAY QYTTLTSIQL LDCFVIPVVI LLSWFFLLIR YKAVHFIGIV VCILGMGCMV GADVLVGRHQ GAGENKLVGD LLVLGGATLY GISNVWEEYI IRTLSRVEFL GMIGLFGAFF SGIQLAIMEH KELLKVPWDW QIGLLYVGFS ACMFGLYSFM PVVIKKTSAT SVNLSLLTAD LYSLFCGLFL FHYKFSGLYL LSFFTILIGL VLYSSTSTYI AQDPRVYKQF RNPSGPVVDL PTTAQVEPSV TYTSLGQETE EEPHVRVA

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC35F1?

The strongest Open Targets associations for SLC35F1 are resting heart rate, atrial fibrillation, QRS duration, hypertension and diastolic blood pressure.

How long is the SLC35F1 protein?

The Homo sapiens SLC35F1 protein (UniProt Q5T1Q4) is 408 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T1Q4
GeneSLC35F1
OrganismHomo sapiens
Length408
Binders0
Diseases47
View on UniProt