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Noncompact myelin-associated protein (NCMAP)

Homo sapiens — UniProt Q5T1S8

Gene: NCMAPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Noncompact myelin-associated protein (NCMAP) is a protein from Homo sapiens identified by UniProt accession Q5T1S8, 102 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

  • UniProt accession: Q5T1S8; gene symbol NCMAP.
  • Organism: Homo sapiens.
  • Length: 102 amino acids.
  • Top disease associations (Open Targets): peak expiratory flow, metabolite measurement and alopecia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameNoncompact myelin-associated protein
UniProt accessionQ5T1S8
GeneNCMAP
OrganismHomo sapiens
Length102 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (23)

Diseases linked to this target (Open Targets).

  • peak expiratory flow · score 0.35
  • metabolite measurement · score 0.11
  • alopecia · score 0.08
  • hair shape measurement · score 0.07
  • deafness · score 0.06
  • Barrett's esophagus · score 0.05
  • cardiovascular disease · score 0.05
  • benign adult familial myoclonic epilepsy · score 0.04
  • esophageal adenocarcinoma · score 0.04
  • breast carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q5T1S8-F1alphafoldPREDICTED65.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T1S8.

Amino-acid sequence (102 residues)

MTTATPLGDT TFFSLNMTTR GEDFLYKSSG AIVAAVVVVV IIIFTVVLIL LKMYNRKMRT RRELEPKGPK PTAPSAVGPN SNGSQHPATV TFSPVDVQVE TR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NCMAP?

The strongest Open Targets associations for NCMAP are peak expiratory flow, metabolite measurement, alopecia, hair shape measurement and deafness.

How long is the NCMAP protein?

The Homo sapiens NCMAP protein (UniProt Q5T1S8) is 102 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ5T1S8
GeneNCMAP
OrganismHomo sapiens
Length102
Binders0
Diseases23
View on UniProt