Zinc finger CCCH domain-containing protein 13 (ZC3H13)

Homo sapiens — UniProt Q5T200

Gene: ZC3H13Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Zinc finger CCCH domain-containing protein 13 (ZC3H13) is a protein from Homo sapiens identified by UniProt accession Q5T200, 1668 residues long. MolForge cross-references it against 0 known binders and 121 disease associations.

UniProt accession: Q5T200; gene symbol ZC3H13.
Organism: Homo sapiens.
Length: 1668 amino acids.
Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and carboxypeptidase B2 measurement.
3D structure: AlphaFold model available.

Target properties

Protein name	Zinc finger CCCH domain-containing protein 13
UniProt accession	Q5T200
Gene	ZC3H13
Organism	Homo sapiens
Length	1668 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (121)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.55
blood protein measurement · score 0.41
carboxypeptidase B2 measurement · score 0.31
glucose measurement · score 0.28
appendicular lean mass · score 0.24
IGF-1 measurement · score 0.24
type 2 diabetes mellitus · score 0.22
mean platelet volume · score 0.21
macrophage migration inhibitory factor measurement · score 0.21
MAP kinase-activated protein kinase 3 measurement · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5T200-F1	alphafold	PREDICTED	46.87	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T200.

Amino-acid sequence (1668 residues)

MSKIRRKVTV ENTKTISDST SRRPSVFERL GPSTGSTAET QCRNWLKTGN CLYGNTCRFV HGPSPRGKGY SSNYRRSPER PTGDLRERMK NKRQDVDTEP QKRNTEESSS PVRKESSRGR HREKEDIKIT KERTPESEEE NVEWETNRDD SDNGDINYDY VHELSLEMKR QKIQRELMKL EQENMEKREE IIIKKEVSPE VVRSKLSPSP SLRKSSKSPK RKSSPKSSSA SKKDRKTSAV SSPLLDQQRN SKTNQSKKKG PRTPSPPPPI PEDIALGKKY KEKYKVKDRI EEKTRDGKDR GRDFERQREK RDKPRSTSPA GQHHSPISSR HHSSSSQSGS SIQRHSPSPR RKRTPSPSYQ RTLTPPLRRS ASPYPSHSLS SPQRKQSPPR HRSPMREKGR HDHERTSQSH DRRHERREDT RGKRDREKDS REEREYEQDQ SSSRDHRDDR EPRDGRDRRD ARDTRDRREL RDSRDMRDSR EMRDYSRDTK ESRDPRDSRS TRDAHDYRDR EGRDTHRKED TYPEESRSYG RNHLREESSR TEIRNESRNE SRSEIRNDRM GRSRGRVPEL PEKGSRGSRG SQIDSHSSNS NYHDSWETRS SYPERDRYPE RDNRDQARDS SFERRHGERD RRDNRERDQR PSSPIRHQGR NDELERDERR EERRVDRVDD RRDERARERD RERERDRERE RERERERDRE REKERELERE RARERERERE KERDRERDRD RDHDRERERE RERDREKERE REREERERER ERERERERER ERERERARER DKERERQRDW EDKDKGRDDR REKREEIRED RNPRDGHDER KSKKRYRNEG SPSPRQSPKR RREHSPDSDA YNSGDDKNEK HRLLSQVVRP QESRSLSPSH LTEDRQGRWK EEDRKPERKE SSRRYEEQEL KEKVSSVDKQ REQTEILESS RMRAQDIIGH HQSEDRETSD RAHDENKKKA KIQKKPIKKK KEDDVGIERG NIETTSEDGQ VFSPKKGQKK KSIEKKRKKS KGDSDISDEE AAQQSKKKRG PRTPPITTKE ELVEMCNGKN GILEDSQKKE DTAFSDWSDE DVPDRTEVTE AEHTATATTP GSTPSPLSSL LPPPPPVATA TATTVPATLA ATTAAAATSF STSAITISTS ATPTNTTNNT FANEDSHRKC HRTRVEKVET PHVTIEDAQH RKPMDQKRSS SLGSNRSNRS HTSGRLRSPS NDSAHRSGDD QSGRKRVLHS GSRDREKTKS LEITGERKSR IDQLKRGEPS RSTSSDRQDS RSHSSRRSSP ESDRQVHSRS GSFDSRDRLQ ERDRYEHDRE RERERRDTRQ REWDRDADKD WPRNRDRDRL RERERERERD KRRDLDRERE RLISDSVERD RDRDRDRTFE SSQIESVKRC EAKLEGEHER DLESTSRDSL ALDKERMDKD LGSVQGFEET NKSERTESLE GDDESKLDDA HSLGSGAGEG YEPISDDELD EILAGDAEKR EDQQDEEKMP DPLDVIDVDW SGLMPKHPKE PREPGAALLK FTPGAVMLRV GISKKLAGSE LFAKVKETCQ RLLEKPKDAD NLFEHELGAL NMAALLRKEE RASLLSNLGP CCKALCFRRD SAIRKQLVKN EKGTIKQAYT SAPMVDNELL RLSLRLFKRK TTCHAPGHEK TEDNKLSQSS IQQELCVS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZC3H13?

The strongest Open Targets associations for ZC3H13 are neurodegenerative disease, blood protein measurement, carboxypeptidase B2 measurement, glucose measurement and appendicular lean mass.

How long is the ZC3H13 protein?

The Homo sapiens ZC3H13 protein (UniProt Q5T200) is 1668 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q5T200 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q5T200 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

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