Trafficking protein particle complex subunit 3-like protein (TRAPPC3L)
Homo sapiens — UniProt Q5T215
Data last refreshed: (UniProt release unknown)
Key facts
Trafficking protein particle complex subunit 3-like protein (TRAPPC3L) is a protein from Homo sapiens identified by UniProt accession Q5T215, 181 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q5T215; gene symbol TRAPPC3L.
- Organism: Homo sapiens.
- Length: 181 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, blood protein measurement and spinal stenosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Trafficking protein particle complex subunit 3-like protein |
|---|---|
| UniProt accession | Q5T215 |
| Gene | TRAPPC3L |
| Organism | Homo sapiens |
| Length | 181 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- blood protein measurement · score 0.12
- spinal stenosis · score 0.10
- ulcerative colitis · score 0.07
- nephrotic syndrome · score 0.06
- sitting height measurement · score 0.03
- neoplasm · score 0.01
- pancreatic carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T215-F1 | alphafold | PREDICTED | 87.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T215.
Amino-acid sequence (181 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRAPPC3L?
The strongest Open Targets associations for TRAPPC3L are neurodegenerative disease, blood protein measurement, spinal stenosis, ulcerative colitis and nephrotic syndrome.
How long is the TRAPPC3L protein?
The Homo sapiens TRAPPC3L protein (UniProt Q5T215) is 181 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T215 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T215 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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