Undifferentiated embryonic cell transcription factor 1 (UTF1)
Homo sapiens — UniProt Q5T230
Data last refreshed: (UniProt release unknown)
Key facts
Undifferentiated embryonic cell transcription factor 1 (UTF1) is a protein from Homo sapiens identified by UniProt accession Q5T230, 341 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q5T230; gene symbol UTF1.
- Organism: Homo sapiens.
- Length: 341 amino acids.
- Top disease associations (Open Targets): testosterone measurement, breast cancer and lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Undifferentiated embryonic cell transcription factor 1 |
|---|---|
| UniProt accession | Q5T230 |
| Gene | UTF1 |
| Organism | Homo sapiens |
| Length | 341 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.08
- breast cancer · score 0.07
- lung carcinoma · score 0.06
- placental insufficiency · score 0.03
- neoplasm · score 0.03
- squamous cell carcinoma · score 0.03
- cancer · score 0.02
- embryonal carcinoma · score 0.01
- carcinoma · score 0.01
- nocardiosis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T230-F1 | alphafold | PREDICTED | 66.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T230.
Amino-acid sequence (341 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UTF1?
The strongest Open Targets associations for UTF1 are testosterone measurement, breast cancer, lung carcinoma, placental insufficiency and neoplasm.
How long is the UTF1 protein?
The Homo sapiens UTF1 protein (UniProt Q5T230) is 341 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T230 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T230 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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