Transmembrane protein 273 (TMEM273)
Homo sapiens — UniProt Q5T292
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 273 (TMEM273) is a protein from Homo sapiens identified by UniProt accession Q5T292, 105 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q5T292; gene symbol TMEM273.
- Organism: Homo sapiens.
- Length: 105 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, leukocyte count and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 273 |
|---|---|
| UniProt accession | Q5T292 |
| Gene | TMEM273 |
| Organism | Homo sapiens |
| Length | 105 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.36
- leukocyte count · score 0.34
- lymphocyte count · score 0.33
- platelet count · score 0.33
- cortical surface area measurement · score 0.25
- atrial flutter · score 0.25
- atrial fibrillation · score 0.25
- neuroimaging measurement · score 0.21
- bilirubin measurement · score 0.21
- calcium measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T292-F1 | alphafold | PREDICTED | 62.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T292.
Amino-acid sequence (105 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM273?
The strongest Open Targets associations for TMEM273 are mean corpuscular volume, leukocyte count, lymphocyte count, platelet count and cortical surface area measurement.
How long is the TMEM273 protein?
The Homo sapiens TMEM273 protein (UniProt Q5T292) is 105 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T292 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T292 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.