OTU domain-containing protein 3 (OTUD3)
Homo sapiens — UniProt Q5T2D3
Data last refreshed: (UniProt release unknown)
Key facts
OTU domain-containing protein 3 (OTUD3) is a protein from Homo sapiens identified by UniProt accession Q5T2D3, 398 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q5T2D3; gene symbol OTUD3.
- Organism: Homo sapiens.
- Length: 398 amino acids.
- Top disease associations (Open Targets): ulcerative colitis, inflammatory bowel disease and low grade glioma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | OTU domain-containing protein 3 |
|---|---|
| UniProt accession | Q5T2D3 |
| Gene | OTUD3 |
| Organism | Homo sapiens |
| Length | 398 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- ulcerative colitis · score 0.31
- inflammatory bowel disease · score 0.28
- low grade glioma · score 0.23
- breast adenocarcinoma · score 0.23
- ulcerative proctosigmoiditis · score 0.19
- endometrial cancer · score 0.18
- gastric adenocarcinoma · score 0.18
- Crohn's disease · score 0.12
- colitis · score 0.10
- enteritis · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T2D3-F1 | alphafold | PREDICTED | 70.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T2D3.
Amino-acid sequence (398 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OTUD3?
The strongest Open Targets associations for OTUD3 are ulcerative colitis, inflammatory bowel disease, low grade glioma, breast adenocarcinoma and ulcerative proctosigmoiditis.
How long is the OTUD3 protein?
The Homo sapiens OTUD3 protein (UniProt Q5T2D3) is 398 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T2D3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T2D3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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