Armadillo-like helical domain-containing protein 3 (ARMH3)
Homo sapiens — UniProt Q5T2E6
Data last refreshed: (UniProt release unknown)
Key facts
Armadillo-like helical domain-containing protein 3 (ARMH3) is a protein from Homo sapiens identified by UniProt accession Q5T2E6, 689 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q5T2E6; gene symbol ARMH3.
- Organism: Homo sapiens.
- Length: 689 amino acids.
- Top disease associations (Open Targets): cognitive function measurement, self reported educational attainment and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Armadillo-like helical domain-containing protein 3 |
|---|---|
| UniProt accession | Q5T2E6 |
| Gene | ARMH3 |
| Organism | Homo sapiens |
| Length | 689 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- cognitive function measurement · score 0.17
- self reported educational attainment · score 0.16
- heel bone mineral density · score 0.14
- mean reticulocyte volume · score 0.13
- pulse pressure measurement · score 0.13
- diet measurement · score 0.12
- lifestyle measurement · score 0.11
- alkaline phosphatase measurement · score 0.10
- atrial fibrillation · score 0.10
- platelet-to-lymphocyte ratio · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T2E6-F1 | alphafold | PREDICTED | 84.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T2E6.
Amino-acid sequence (689 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARMH3?
The strongest Open Targets associations for ARMH3 are cognitive function measurement, self reported educational attainment, heel bone mineral density, mean reticulocyte volume and pulse pressure measurement.
How long is the ARMH3 protein?
The Homo sapiens ARMH3 protein (UniProt Q5T2E6) is 689 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T2E6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T2E6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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