About Outer dynein arm-docking complex subunit 2
Outer dynein arm-docking complex subunit 2 (ODAD2) is a protein
from Homo sapiens identified by UniProt accession
Q5T2S8, 1044 residues long.
MolForge cross-references it against 0 known binders and
155 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (155)
Diseases linked to this target (Open Targets).
- primary ciliary dyskinesia · score 0.71
- systolic blood pressure · score 0.46
- vital capacity · score 0.41
- body height · score 0.41
- male infertility · score 0.40
- diastolic blood pressure · score 0.39
- hypertension · score 0.39
- sitting height measurement · score 0.34
- creatinine measurement · score 0.33
- cardiovascular disease · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q5T2S8.
Amino-acid sequence (1044 residues)
MGVALRKLTQ WTAAGHGTGI LEITPLNEAI LKEIIVFVES FIYKHPQEAK FVFVEPLEWN TSLAPSAFES GYVVSETTVK SEEVDKNGQP LLFLSVPQIK IRSFGQLSRL LLIAKTGKLK EAQACVEANR DPIVKILGSD YNTMKENSIA LNILGKITRD DDPESEIKMK IAMLLKQLDL HLLNHSLKHI SLEISLSPMT VKKDIELLKR FSGKGNQTVL ESIEYTSDYE FSNGCRAPPW RQIRGEICYV LVKPHDGETL CITCSAGGVF LNGGKTDDEG DVNYERKGSI YKNLVTFLRE KSPKFSENMS KLGISFSEDQ QKEKDQLGKA PKKEEAAALR KDISGSDKRS LEKNQINFWR NQMTKRWEPS LNWKTTVNYK GKGSAKEIQE DKHTGKLEKP RPSVSHGRAQ LLRKSAEKIE ETVSDSSSES EEDEEPPDHR QEASADLPSE YWQIQKLVKY LKGGNQTATV IALCSMRDFS LAQETCQLAI RDVGGLEVLI NLLETDEVKC KIGSLKILKE ISHNPQIRQN IVDLGGLPIM VNILDSPHKS LKCLAAETIA NVAKFKRARR VVRQHGGITK LVALLDCAHD STKPAQSSLY EARDVEVARC GALALWSCSK SHTNKEAIRK AGGIPLLARL LKTSHENMLI PVVGTLQECA SEENYRAAIK AERIIENLVK NLNSENEQLQ EHCAMAIYQC AEDKETRDLV RLHGGLKPLA SLLNNTDNKE RLAAVTGAIW KCSISKENVT KFREYKAIET LVGLLTDQPE EVLVNVVGAL GECCQERENR VIVRKCGGIQ PLVNLLVGIN QALLVNVTKA VGACAVEPES MMIIDRLDGV RLLWSLLKNP HPDVKASAAW ALCPCIKNAK DAGEMVRSFV GGLELIVNLL KSDNKEVLAS VCAAITNIAK DQENLAVITD HGVVPLLSKL ANTNNNKLRH HLAEAISRCC MWGRNRVAFG EHKAVAPLVR YLKSNDTNVH RATAQALYQL SEDADNCITM HENGAVKLLL DMVGSPDQDL QEAAAGCISN IRRLALATEK ARYT
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