MAGUK p55 subfamily member 7 (MPP7)
Homo sapiens — UniProt Q5T2T1
Data last refreshed: (UniProt release unknown)
Key facts
MAGUK p55 subfamily member 7 (MPP7) is a protein from Homo sapiens identified by UniProt accession Q5T2T1, 576 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q5T2T1; gene symbol MPP7.
- Organism: Homo sapiens.
- Length: 576 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, Achilles tendon injury and bone quantitative ultrasound measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MAGUK p55 subfamily member 7 |
|---|---|
| UniProt accession | Q5T2T1 |
| Gene | MPP7 |
| Organism | Homo sapiens |
| Length | 576 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.48
- Achilles tendon injury · score 0.40
- bone quantitative ultrasound measurement · score 0.40
- bone density · score 0.38
- appendicular lean mass · score 0.32
- macula measurement · score 0.30
- spine bone mineral density · score 0.28
- sitting height measurement · score 0.23
- metabolite measurement · score 0.19
- protein measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T2T1-F1 | alphafold | PREDICTED | 80.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T2T1.
Amino-acid sequence (576 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MPP7?
The strongest Open Targets associations for MPP7 are heel bone mineral density, Achilles tendon injury, bone quantitative ultrasound measurement, bone density and appendicular lean mass.
How long is the MPP7 protein?
The Homo sapiens MPP7 protein (UniProt Q5T2T1) is 576 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T2T1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T2T1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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