ATP-binding cassette sub-family C member 10 (ABCC10)
Homo sapiens — UniProt Q5T3U5
Data last refreshed: (UniProt release unknown)
Key facts
ATP-binding cassette sub-family C member 10 (ABCC10) is a protein from Homo sapiens identified by UniProt accession Q5T3U5, 1492 residues long. MolForge cross-references it against 5 known binders and 86 disease associations.
- UniProt accession: Q5T3U5; gene symbol ABCC10.
- Organism: Homo sapiens.
- Length: 1492 amino acids.
- Top disease associations (Open Targets): toll-like receptor 2 measurement, diastolic blood pressure and age-related hearing impairment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-binding cassette sub-family C member 10 |
|---|---|
| UniProt accession | Q5T3U5 |
| Gene | ABCC10 |
| Organism | Homo sapiens |
| Length | 1492 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- toll-like receptor 2 measurement · score 0.17
- diastolic blood pressure · score 0.17
- age-related hearing impairment · score 0.14
- mathematical ability · score 0.11
- non-small cell lung carcinoma · score 0.09
- neoplasm · score 0.09
- platelet count · score 0.08
- body height · score 0.08
- breast cancer · score 0.07
- Gorham-Stout disease · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T3U5-F1 | alphafold | PREDICTED | 80.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T3U5.
Amino-acid sequence (1492 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABCC10?
The strongest Open Targets associations for ABCC10 are toll-like receptor 2 measurement, diastolic blood pressure, age-related hearing impairment, mathematical ability and non-small cell lung carcinoma.
How long is the ABCC10 protein?
The Homo sapiens ABCC10 protein (UniProt Q5T3U5) is 1492 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T3U5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T3U5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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