Inactive glycosyltransferase 25 family member 3 (CERCAM)
Homo sapiens — UniProt Q5T4B2
Data last refreshed: (UniProt release unknown)
Key facts
Inactive glycosyltransferase 25 family member 3 (CERCAM) is a protein from Homo sapiens identified by UniProt accession Q5T4B2, 595 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q5T4B2; gene symbol CERCAM.
- Organism: Homo sapiens.
- Length: 595 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neoplasm and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inactive glycosyltransferase 25 family member 3 |
|---|---|
| UniProt accession | Q5T4B2 |
| Gene | CERCAM |
| Organism | Homo sapiens |
| Length | 595 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- neoplasm · score 0.09
- head and neck squamous cell carcinoma · score 0.08
- urinary bladder carcinoma · score 0.08
- cancer · score 0.03
- pulse pressure measurement · score 0.03
- esophageal squamous cell carcinoma · score 0.03
- cystatin C measurement · score 0.02
- creatinine measurement · score 0.02
- body mass index · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T4B2-F1 | alphafold | PREDICTED | 88.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T4B2.
Amino-acid sequence (595 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CERCAM?
The strongest Open Targets associations for CERCAM are neurodegenerative disease, neoplasm, head and neck squamous cell carcinoma, urinary bladder carcinoma and cancer.
How long is the CERCAM protein?
The Homo sapiens CERCAM protein (UniProt Q5T4B2) is 595 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T4B2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T4B2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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