Synaptonemal complex protein 2-like (SYCP2L)
Homo sapiens — UniProt Q5T4T6
Data last refreshed: (UniProt release unknown)
Key facts
Synaptonemal complex protein 2-like (SYCP2L) is a protein from Homo sapiens identified by UniProt accession Q5T4T6, 812 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q5T4T6; gene symbol SYCP2L.
- Organism: Homo sapiens.
- Length: 812 amino acids.
- Top disease associations (Open Targets): age at menopause, menopause and age at menarche.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptonemal complex protein 2-like |
|---|---|
| UniProt accession | Q5T4T6 |
| Gene | SYCP2L |
| Organism | Homo sapiens |
| Length | 812 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- age at menopause · score 0.45
- menopause · score 0.31
- age at menarche · score 0.30
- neurodegenerative disease · score 0.28
- docosahexaenoic acid measurement · score 0.23
- fatty acid measurement · score 0.22
- hyperparathyroidism · score 0.19
- Premature ovarian insufficiency · score 0.18
- benign neoplasm of parathyroid gland · score 0.16
- parathyroid disease · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T4T6-F1 | alphafold | PREDICTED | 65.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T4T6.
Amino-acid sequence (812 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYCP2L?
The strongest Open Targets associations for SYCP2L are age at menopause, menopause, age at menarche, neurodegenerative disease and docosahexaenoic acid measurement.
How long is the SYCP2L protein?
The Homo sapiens SYCP2L protein (UniProt Q5T4T6) is 812 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T4T6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T4T6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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