Artemin (ARTN)
Homo sapiens — UniProt Q5T4W7
Data last refreshed: (UniProt release unknown)
Key facts
Artemin (ARTN) is a protein from Homo sapiens identified by UniProt accession Q5T4W7, 220 residues long. MolForge cross-references it against 0 known binders and 121 disease associations.
- UniProt accession: Q5T4W7; gene symbol ARTN.
- Organism: Homo sapiens.
- Length: 220 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, intelligence and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Artemin |
|---|---|
| UniProt accession | Q5T4W7 |
| Gene | ARTN |
| Organism | Homo sapiens |
| Length | 220 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (121)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- intelligence · score 0.14
- self reported educational attainment · score 0.12
- blood protein measurement · score 0.10
- age at first birth measurement · score 0.10
- verbal-numerical reasoning measurement · score 0.10
- attention deficit hyperactivity disorder · score 0.09
- neoplasm · score 0.08
- hepatocellular carcinoma · score 0.08
- gonorrhea · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T4W7-F1 | alphafold | PREDICTED | 74.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T4W7.
Amino-acid sequence (220 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARTN?
The strongest Open Targets associations for ARTN are neurodegenerative disease, intelligence, self reported educational attainment, blood protein measurement and age at first birth measurement.
How long is the ARTN protein?
The Homo sapiens ARTN protein (UniProt Q5T4W7) is 220 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T4W7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T4W7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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