Late cornified envelope protein 3C (LCE3C)
Homo sapiens — UniProt Q5T5A8
Data last refreshed: (UniProt release unknown)
Key facts
Late cornified envelope protein 3C (LCE3C) is a protein from Homo sapiens identified by UniProt accession Q5T5A8, 94 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q5T5A8; gene symbol LCE3C.
- Organism: Homo sapiens.
- Length: 94 amino acids.
- Top disease associations (Open Targets): psoriasis, type 2 diabetes mellitus and ankylosing spondylitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Late cornified envelope protein 3C |
|---|---|
| UniProt accession | Q5T5A8 |
| Gene | LCE3C |
| Organism | Homo sapiens |
| Length | 94 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- psoriasis · score 0.10
- type 2 diabetes mellitus · score 0.04
- ankylosing spondylitis · score 0.03
- Crohn's disease · score 0.03
- sclerosing cholangitis · score 0.03
- ulcerative colitis · score 0.03
- psoriasis vulgaris · score 0.03
- Rheumatoid arthritis · score 0.01
- allergic contact dermatitis · score 0.01
- psoriatic arthritis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T5A8-F1 | alphafold | PREDICTED | 56.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5A8.
Amino-acid sequence (94 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LCE3C?
The strongest Open Targets associations for LCE3C are psoriasis, type 2 diabetes mellitus, ankylosing spondylitis, Crohn's disease and sclerosing cholangitis.
How long is the LCE3C protein?
The Homo sapiens LCE3C protein (UniProt Q5T5A8) is 94 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T5A8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T5A8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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