Late cornified envelope protein 3E (LCE3E)
Homo sapiens — UniProt Q5T5B0
Data last refreshed: (UniProt release unknown)
Key facts
Late cornified envelope protein 3E (LCE3E) is a protein from Homo sapiens identified by UniProt accession Q5T5B0, 92 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q5T5B0; gene symbol LCE3E.
- Organism: Homo sapiens.
- Length: 92 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, breast adenocarcinoma and prostate adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Late cornified envelope protein 3E |
|---|---|
| UniProt accession | Q5T5B0 |
| Gene | LCE3E |
| Organism | Homo sapiens |
| Length | 92 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.21
- ovarian cancer · score 0.18
- psoriasis · score 0.18
- primary biliary cirrhosis · score 0.15
- squamous cell lung carcinoma · score 0.11
- esophageal adenocarcinoma · score 0.04
- vitamin D measurement · score 0.04
- atopic eczema · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T5B0-F1 | alphafold | PREDICTED | 58.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5B0.
Amino-acid sequence (92 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LCE3E?
The strongest Open Targets associations for LCE3E are glioblastoma multiforme, breast adenocarcinoma, prostate adenocarcinoma, ovarian cancer and psoriasis.
How long is the LCE3E protein?
The Homo sapiens LCE3E protein (UniProt Q5T5B0) is 92 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T5B0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T5B0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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