Zinc finger protein 684 (ZNF684)
Homo sapiens — UniProt Q5T5D7
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 684 (ZNF684) is a protein from Homo sapiens identified by UniProt accession Q5T5D7, 378 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q5T5D7; gene symbol ZNF684.
- Organism: Homo sapiens.
- Length: 378 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, pancreatic adenocarcinoma and heart disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 684 |
|---|---|
| UniProt accession | Q5T5D7 |
| Gene | ZNF684 |
| Organism | Homo sapiens |
| Length | 378 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- pancreatic adenocarcinoma · score 0.14
- heart disease · score 0.05
- Chronic Obstructive Asthma · score 0.02
- systemic lupus erythematosus · score 0.01
- hepatitis B virus induced hepatocellular carcinoma · score 0.00
- infectious disease · score 0.00
- COVID-19 · score 0.00
- pancreatic ductal adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q5T5D7-F1 | alphafold | PREDICTED | 72.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q5T5D7.
Amino-acid sequence (378 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF684?
The strongest Open Targets associations for ZNF684 are neurodegenerative disease, pancreatic adenocarcinoma, heart disease, Chronic Obstructive Asthma and systemic lupus erythematosus.
How long is the ZNF684 protein?
The Homo sapiens ZNF684 protein (UniProt Q5T5D7) is 378 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q5T5D7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q5T5D7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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